Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKB All Species: 13.33
Human Site: S295 Identified Species: 22.56
UniProt: Q96GD4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96GD4 NP_004208.2 344 39280 S295 V D L K F P A S V P T G A Q D
Chimpanzee Pan troglodytes XP_511856 395 44529 S346 V D L K F P A S V P T G A Q D
Rhesus Macaque Macaca mulatta XP_001118154 562 62706 S513 V D L K F P A S V P T G A Q D
Dog Lupus familis XP_849906 346 39574 S297 V D L K F P P S V P T G A Q D
Cat Felis silvestris
Mouse Mus musculus O70126 345 39306 K292 E T Y R R I V K V D L K F P S
Rat Rattus norvegicus O55099 343 39216 K290 E T Y R R I V K V D L K F P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521399 303 34973 F250 V E Y K F P G F V T D G A K D
Chicken Gallus gallus XP_425725 409 46456 R357 E T Y R A I S R V E F K Y P L
Frog Xenopus laevis Q6DE08 361 41717 F311 V D L K F P P F L S D G S K D
Zebra Danio Brachydanio rerio Q6NW76 320 36928 L271 V D L Q F P K L V S E G A R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKN7 329 38282 H273 M E I S Y P S H L S K G C K E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O01427 305 34731 I257 K K G A R D L I G R L L V V D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M077 294 33954 P246 V Q V D L K F P P K P I I S A
Baker's Yeast Sacchar. cerevisiae P38991 367 42927 I318 K R I A A L D I K M P S N I S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.8 60.3 91.3 N.A. 84.9 84.5 N.A. 61.9 56.9 67.5 66.5 N.A. 44.4 N.A. 53.4 N.A.
Protein Similarity: 100 86.3 60.6 95 N.A. 91.5 90.4 N.A. 72 66.5 78.6 76.1 N.A. 62.5 N.A. 65.1 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 6.6 6.6 N.A. 53.3 6.6 53.3 60 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 13.3 N.A. 66.6 20 73.3 73.3 N.A. 66.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 54.9 36.7 N.A.
Protein Similarity: N.A. N.A. N.A. 68 59.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 15 0 22 0 0 0 0 0 43 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 43 0 8 0 8 8 0 0 15 15 0 0 0 58 % D
% Glu: 22 15 0 0 0 0 0 0 0 8 8 0 0 0 8 % E
% Phe: 0 0 0 0 50 0 8 15 0 0 8 0 15 0 0 % F
% Gly: 0 0 8 0 0 0 8 0 8 0 0 58 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 15 0 0 22 0 15 0 0 0 8 8 8 0 % I
% Lys: 15 8 0 43 0 8 8 15 8 8 8 22 0 22 0 % K
% Leu: 0 0 43 0 8 8 8 8 15 0 22 8 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 58 15 8 8 29 15 0 0 22 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 29 0 % Q
% Arg: 0 8 0 22 22 0 0 8 0 8 0 0 0 8 0 % R
% Ser: 0 0 0 8 0 0 15 29 0 22 0 8 8 8 22 % S
% Thr: 0 22 0 0 0 0 0 0 0 8 29 0 0 0 0 % T
% Val: 58 0 8 0 0 0 15 0 65 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 29 0 8 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _